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Published hypotheses include interaction with one or more NOS isoforms, changes in NOS phosphorylation, effects on NOS cofactor availability, altered oxidative inactivation of NO, or a combination of mechanisms that depend on cell type and experimental context

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8.4 Pediatric Use Treatment of Acute Pain The safety and effectiveness of acetaminophen for the treatment of acute pain in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of acetaminophen in adults and safety and pharmacokinetic data from adult and 483 pediatric patients across all age groups [see DOSAGE AND ADMINISTRATION (2.3) and PHARMACOKINETICS (12.3)]

Enhanced Nerve Repair : Shown in studies to support remyelination faster than cyanocobalamin

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Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo