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Lipid peroxidation products can be recognized by DCs as DAMPs, activating the TLR4 and NLRP3 inflammasome pathways, and intensifying local immune dysregulation (56)

GH = growth hormone, GHRH = growth hormone releasing hormone, IGF = insulin-like growth factor, PI3K = phosphoinositide 3-kinase, AKT = protein kinase B, mTOR = mammalian target of rapamycin, FoxO = forkhead box O, AOD = anti-obesity drug, AMPK = AMP-activated protein kinase

The species results of these two methods were cross-compared and a result was only considered definitive if it was identified using both methodologies

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Such testing assesses the function of the middle and inner ear structures and can help detect and quantify hearing loss