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Cell transplantation Mesenchymal stem cells (MSCs) can differentiate into various musculoskeletal cell types and, therefore, are emerging as frontiers in regenerative medicine for musculoskeletal disorders including CDLBP, due to their antiinflammatory, immunosuppressive properties

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Additionally, cyclosporine exerts adverse effects on liver function and redox balance responses in treated rats, as evidenced by its increasing levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and bilirubin while also decreasing the levels of glutathione and NADPH