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IGF axis activity associates with deregulated immune genes and immune infiltrating cells in PCa tissues To test the clinical relevance of these findings we interrogated public RNA-seq data from the Prostate Adenocarcinoma Firehose Legacy dataset in cbioportal (www.cbioportal.org/study/summary?id=prad_tcga) 30

Front Endocrinol (Lausanne) (2019) 10:482

doi: 10.1016/s0891-5849(01)00719-5

PLoS One 8 , e55407 (2013)

No statistically significant difference was observed in the rate of moderate-to-severe exacerbations between the treatment and placebo arms (0.68 versus 0.59 exacerbations/patient/year, p =0.054)

[DOI] [PubMed] [Google Scholar] 81.Guix F.X., Ill-Raga G., Bravo R., Nakaya T., de Fabritiis G., Coma M., Miscione G.P., Vill-Freixa J., Suzuki T., Fernndez-Busquets X., et al