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As a result, the nanoplatform exhibited stealth properties and active targeting ability [152]

The duration of the therapeutic effect is dictated by the residency time of the drug within the lung/receptor site, which can be manipulated by changing the chemical properties of the drugs delivered via inhaled delivery devices (Labiris and Dolovich 2003)

On the other hand, cellular release of zinc in the brain can mediate neuronal apoptosis and may be pathologically associated with Alzheimers disease and amyotrophic lateral sclerosis (ALS) (80)

Further, the induction of NQO1 up to 30-fold is possible in response to oxidative stress generated by UV radiation and X-rays in human cells [38,43]

[DOI] [Google Scholar] Safarov R., Fedotova O., Uvarova A., Gordienko M., Menshutina N