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82 KurodaM.KatoY.YamazakiJ.KaiY.MizukoshiT.MiyanoH.et al (2012)
PPAR activator has been previously reported to protect against acetaminophen-induced hepatotoxicity, but fenofibrate, a lipid-lowering drug that activates PPAR, has a common side-effect causing liver injury
In copper-iron metabolic competition, copper overload inhibits TfR1, leading to iron accumulation in neurons and activation of ferroptosis
Adipose tissue, particularly visceral fat, secretes adipokines and cytokines that exacerbate inflammation
Stockler-Ipsiroglu et al, 2014
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