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However, excessive excitatory action of glutamate may cause excitotoxic neuronal damage as a result of a sustained influx of extracellular calcium ions (Ca 2+ ) [109, 110]

The interaction between SiO 2 nanoparticles, catalase (CAT), and human mesenchymal stem cells (hMSCs) was meticulously investigated by Mousavi and colleagues in 2019 through a comprehensive approach involving cellular assays, molecular docking, dynamics studies, and various spectroscopic techniques
(PubMed) Yes allergic reactions from mild rash/itching to severe anaphylaxis have been reported
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

J Biol Chem (2002) 277(22):1958593

Gr-1+Cd115+ Immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
