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The start year 1999 was selected as it marks the period following the widespread adoption of the Rotterdam and NIH criteria for PCOS diagnosis, which provided greater consistency in defining study populations

Microglia then break down ATP into adenosine, which binds to adenosine receptors on the surface of active neurons

Research-grade 5-Amino-1MQ refers to laboratory-use material tested for purity, analytical consistency, and controlled research applications

Aggregates of mutant polyQ proteins can be taken up by mitochondria, resulting in diminished mitophagy and aggravated mitochondrial dysfunction, subsequently leading to the increased production of reactive oxygen species (ROS) 7 and oxidative stress

Dimensionality reduction and louvain agglomerative hierarchical clustering for cluster-specified frequent biomarker discovery in single-cell sequencing data

Some neurological effects improve with sustained abstinence