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Beppu K, Inokuchi K, Koyanagi N, Nakayama S, Sakata H, Kitano S, et al

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Best Pract Res Clin Endocrinol Metab 35: 101545, 2021

Mitochondrial dysfunction is a key factor in obesity-related metabolic disorders, contributing to increased oxidative stress and impaired energy metabolism

Most importantly, these problems did not improve at all with diet or exercise

proposed that the combination of blue, gray, or white color with structureless zones is a strong indicator for malignancy of mucosal pigmented lesions.[16] However, VL should be an exception to the rule because, in our data, structureless patterns, white structures, and blue color were not uncommon in VL