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Lactate and other metabolites released by CAFs can suppress cytotoxic T cell function and promote regulatory T cell expansion, contributing to immune evasion

Patients with doses 0.5 and 0.8 mg achieved the on state, with the mean duration 40 and 20 min, respectively

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Results showed that BCSO and nanoemulsion formulation significantly downregulated IL-1, TLR4, BAX , and BCL-2 compared to the LPS group (Figure 2)

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