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Tranexamic acid controls melanogenesisthe process by which the skin produces dark pigmentthereby helping to effectively brighten existing dark circles

NADPH levels were measured using an NADP/NADPH Colorimetric Quantification Kit, and acetyl-CoA levels using the PicoProbe Acetyl-CoA Fluorometric Assay Kit (Biovision) following the manufacturers protocols, with the addition of 6N perchloric acid to precipitate proteins

Montalban-Bravo G, Benton CB, Kanagal-Shamanna R, Sasaki K, Assi R, Kadia TM, Ravandi F, Ganan-Gomez I, Cortes JE, Daver NG, Takahashi K, DiNardo CD, Jabbour EJ, Borthakur G, Pemmaraju N, Konopleva MY, Pierce SA, Bueso-Ramos CE, Kornblau SM, Patel K, Colla S, Kantarjian HM, Andreeff MA, Garcia-Manero G

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