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A two-year clinical trial designed to assess the effect of lipoic acid (1,200 mg/day) on loss of mobility and changes in brain volume in patients with progressive multiple sclerosis is ongoing (85)

In addition, Cu toxicity affects the oxygen evolution complex and cytochrome b559

Safety: The trail to the Great Cavern is narrow and can be slippery on rainy days, so caution is recommended

SmithRONinchojiTGordonEAndreHDejanaEVestweberDet al

doi: 10.1002/hep.30852 170 WuRYuITokumaruYAsaokaMOshiMYanLet al

Monitoring Recommendations For extended use protocols, periodic laboratory monitoring provides additional safety assurance

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