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Attenuation of Abeta-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress

4 (1), e001138

These findings indicate that ER stress can regulate melanogenesis and activate the innate immune response, aggravating the pathological process of vitiligo

For example, an engineered Saccharomyces cerevisiae strain produces lactate that exerts dual actions: it inhibits macrophage NLRP3 inflammasome signaling, thereby attenuating inflammation, and serves as a cross-feeding substrate for select commensals, promoting beneficial taxa (e.g., Oscillibacter ) while constraining potentially harmful taxa (e.g., Streptococcus

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Endocrine Pract