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The 2023 Cochrane review concluded that evidence does not support routine use for acute ischemic stroke, highlighting the need for higher-quality studies

J Biol Chem 283: 3437434383 [DOI] [PMC free article] [PubMed] [Google Scholar] Schaeper U., Gehring N.H., Fuchs K.P., Sachs M., Kempkes B., Birchmeier W

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To support these propositions, some studies have found other mitochondrial dysfunctions responsible for the differential presentation of disease in patients with ASD

AGEs are also involved in the inflammatory process by stimulating macrophage activation and secretion of various cytokines through interaction with their receptor (RAGE)