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Su H, Newman E

Moreover, the TGF-beta signaling pathway regulates a broad spectrum of cellular functions such as proliferation, apoptosis, differentiation and migration (63)

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This specific gene provides the instructions for making an enzyme that is critical for processing amino acids and converting inactive forms of folate and Vitamin B12 into their active, methylated forms

These mutations induce mevalonate-5-phosphate (MVP) production, and in turn, MVP promotes mutant p53 stabilization, triggering positive feedback regulation of SREBPs 42

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