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The analysis was done after the fact rather than as a primary endpoint, and the clocks were measured in blood, so they track systemic aging rather than the brain in particular

A better understanding of resistance mechanisms would aid in the development of novel strategies to overcome tamoxifen resistance and provide the basis for breast cancer treatment options

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doi: 10.2337/dc06-9912 118 SchwartzSFonsecaVBernerBCramerMChiangY-KLewinA

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