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The absence of FDA approval means that use represents an off-label application requiring informed consent and medical judgment

(2008) reviewed the anti-inflammatory properties of -MSH-derived peptides, including KPV

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No mice were excluded from any analyses

Concluding Remarks The development of non-cytotoxic anti-CD38 antibodies and small molecules targeting the NADase enzymatic activity of CD38 may present as an important advancement in therapies for cancers and age-related diseases, but many important questions remain about CD38 biology and potential therapeutic uses (see outstanding questions)