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Other gene sets and pathways relate to oxidative damage and other inflammatory mediator pathways such as tumor necrosis factor alpha and interleukin-18 (Supplementary Table S3)
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The physiological role of SLC25A2, which also has an affinity for homoarginine, is unclear [29]
doi: 10.1016/j.clinbiochem.2007.05.021 38 LeverM.SizelandP
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When fibrillin is mutated, such modulating function is missing and TGF- is overexpressed, thereby increasing the activation of its signaling pathway
