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ChIP assay and luciferase reporter assay further revealed that SOX2 directly upregulated Dickkopf WNT Signalling Pathway Inhibitor 1 (DKK1), thus antagonizing the WNT signalling pathway, which is a critical switch in enhancing osteogenesis and inhibiting adipogenesis [29]

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Another study finds that when human coronary artery endothelial cells (HCAECs) are stimulated with high concentrations of copper (50 M CuCl2), the process of cuproptosis is activated, leading to the death or dysfunction of HCAECs

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Jian-Kang Chen, pathologist and kidney researcher in the MCG Department of Cellular Biology and Anatomy, measured T cell infiltration in the chronic models