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In Vivo Summary Keywords autoprocessing, bacteria, catalytic mechanism, -glutamyl transpeptidase, -glutamyl peptides, glutathione, poly--glutamic acid Citation Saini M, Kashyap A, Bindal S, Saini K and Gupta R (2021) Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into StructureFunction Relationship and Its Biotechnological Applications

4.5 Metabolic dysregulation 4.5.1 Insulin signaling pathways in obesity and metabolic disease Metabolic tissues develop lipid intermediates alongside altered adipokine expression profiles and compromised mitochondrial function, progressively attenuating insulin responsiveness (158)

In order to decrease the amount of tau phosphorylation and the formation of neurofibrillary tangles, siRNA against microtubule-associated protein tau (MAPT) has been shown to have a protective effect on synapse function and neuronal survival (101)

GenBank AA305820 EST176819 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end, mRNA sequence

doi: 10.1016/j.foodchem.2019.125109 323 ZhangY.WangL

Trends in Plant Science 20, 807813