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The first approach used only the adjudicated cases (GLP-1 n = 13 and placebo n = 5)

Med Sci Monit 2011;17:BR35-41.ArticlePubMedPMC 104

These findings suggest potential neuroprotective benefits of semaglutide, especially regarding cognitive health, and call for further research to validate its use in treating cognitive deficits and substance misuse in patients with T2DM (87)

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(4) Although our primary focus was on GLP-1 RAs, we included trials evaluating agents with overlapping mechanisms, such as tirzepatide (dual GIP/GLP-1 RA) and cagrilintide (long-acting amylin analogue), due to their emerging relevance in obesity treatment