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This alteration can cause damage to the colonic mucus barrier and result in the development of colitis caused by the enteric pathogen Citrobacter rodentium [136]

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26 There are multiple species with worldwide distribution

Among these, BPC-157 (Body Protection Compound-157), a synthetic peptide derived from a protective protein found in gastric juice, has garnered significant attention for its remarkable regenerative and anti-inflammatory properties

Thus, upon careful selection of the MOA, the inclusion of ferroptosis-inducing agents within a clinically relevant treatment protocol is feasible and can outperform standard-of-care chemotherapy in high-risk NB

Maldonado Galdeano et al., 2019