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doi: 10.1006/exer.1996.0188

Nature 414, 562565

In addition to its critical role in the survival of sensory neurons and neurite outgrowth, NGF signalling is also involved in nociception by activating nociceptive neurons, which express high-affinity NGF receptors [27]

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However, one study demonstrated that treatment with acetyl-L-Carnitine restored the expression and activity of SIRT3, consequently improving mitochondrial function [74]
