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All brain cell types including neurons are able to uptake and metabolize ketones to acetyl-CoA to support the cell energy 46

Higher serum levels of soluble CD14 were detected in patients with TS and bacterial infections [57]

As per a recent study by Wang et al., the overall prevalence rate of OSMF is about 3% (95% CI 2.8%3.2%) worldwide and 4% (95% CI 3.7%4.3%) in India (Wang et al., 2024a)

These compensatory pathways can serve as promising targets for combination therapy

The associated enzymes are discussed as follows and the related genes are listed in Table 1

There is evidence that many genes express themselves differently depending on the stage at which these crucial early developmental events occur