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[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Hadjadj J., Yatim N., Barnabei L., Corneau A., Boussier J., Smith N., Pr H., Charbit B., Bondet V., Chenevier-Gobeaux C., Breillat P., Carlier N., Gauzit R., Morbieu C., Pne F., Marin N., Roche N., Szwebel T.-A., Merkling Sarah H., Treluyer J.-M., Veyer D., Mouthon L., Blanc C., Tharaux P.-L., Rozenberg F., Fischer A., Duffy D., Rieux-Laucat F., Kernis S., Terrier B

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For instance, analyses of proteomemetabolome interactions have suggested that complement factor C3a (C3a) and lysophosphatidylcholine (LysoPC)may form a positive feedback loop and act synergistically in vascular endothelial injury ( Importantly, multi-omics integration suggests that immune dysregulation may emerge from coordinated alterations across genomic, epigenetic, transcriptomic, and metabolic layers rather than isolated pathway changes

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