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Small molecules such as carbohydrates, amino acids, and hormones pass across the BBB using endothelial carrier-mediated transporters (Oldendorf, 1971), while macromolecules such as transferrin and insulin use endothelial receptor-mediated transport (Banks, 2012)

These are genes involved in the effects on host immunity, telomerase, epithelial barrier, and cell replication (Fingerlin et al ., 2013

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Furthermore, Mohajerani et al

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Lipid peroxidation processes can be induced by excess levels of ROS and lead to ferroptosis (31)