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Antimetastatic activity of insulin-like growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition

The product underwent in vitro and in vivo testing (including animal and human studies) and was found to be safe and effective [103, 104]

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Caytaxin, a neuron-specific protein linked to microtubule dynamics, interacts with RAB6 and has been proposed to function as an adaptor connecting mitochondria to the microtubule-based transport machinery [66]

however, it is not known whether this occurs at clinically relevant doses in humans