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[40] With the knowledge of the dopaminergic stimulant effects of the adamantane derivatives, bromantane, which is 2-(4-bromophenylamino) adamantane, was developed in the 1980s at the Zakusov State Institute of Pharmacology, USSR Academy of Medical Sciences (now the Russian Academy of Medical Sciences) in Moscow as "a drug having psychoactivating and adaptogen properties under complicated conditions (hypoxia, high environmental temperature, physical overfatigue, emotional stress, etc.)"

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Crucially, this criterion applies equally well to existing molecules and to new (never synthesised) species, provided a sufficient degree of structural similarity can be identified among them

doi: 10.1093/aob/mcm079
doi: 10.1016/j.mtbio.2023.100918 103

Observational studies have demonstrated that selenium deficiency is linked to an increased risk of cancer
