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Description
Bagcchi S
Am J Psychiatry (2009) 166(4):4509
Molecular mechanisms of membrane targeting antibiotics
In AD, EAAT2 downregulation leads to overactivation, Ca 2+ overload, tau hyperphosphorylation, and dendritic spine collapse
However, challenges persist in applying these approaches in clinical practice
The 15-residue synthetic fragment was numbered 157 within the original research nomenclature used by the discovering group, producing the BPC-157 designation that subsequently became the standard name in published literature
