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Using Pt GSTF8 from poplar as a model enzyme, we use biochemical, structural and computational methods to demonstrate that arGSTs employ a GSH-dependent Brnsted base mechanism for conversion of the LDOX product flavan-3,3,4-triol ( 4 ) or flavan-3-on-4-ol ( 7 ) into flav-2-en-3,4-diol ( 8-B4 ), an equilibrium form of cyanidin

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For instance, one single can of one of the most consumed brand of EDs (Red Bull, 250 mL) contains 80 mg of caffeine (or 0.32 mg/mL) and 1000 mg of taurine (or 4 mg/mL) as major components

Chaudhuri A, Bowling K, Funderburk C, Lawal H, Inamdar A, Wang Z, O'Donnell JM (2007) Interaction of genetic and environmental factors in a Drosophila parkinsonism model

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