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Replica versions began to emerge but have since been banned amid safety concerns, and availability of new drugs targeted for weight loss, Wegovy and Mounjaro, has been expanded

The effect of GLP-1 agonist drugs in reducing RVO compared to DPP-4 inhibitors may largely stem from a reduced risk of BRVO but not central RVO (CRVO)

For tirzepatide, this historically meant preparing lyophilized vials or pre-mixed solutions at various concentrations, sometimes with added compounds like vitamin B12 , glycine , or niacinamide