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The endocannabinoid system is known to be involved in various digestive disorders, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD)

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They found that TGF- 1 was differentially overexpressed in varicose veins with greater expression in the tortuous segments compared with the nontortuous segments of the varicose vein

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(VII) miRNAs directly degrade messenger RNA or repress translation to regulate gene expression (Zhang et al., 2019)

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