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Genetic Findings of GSH GS deficiency is a rare disorder of glutathione (GSH) metabolism manifested in children by severe metabolic acidosis with high urinary level of 5-oxoproline (pyroglutamic acid), hemolytic anemia, and neurological events

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The oxidative burden increases glomerular hypertension and mesangial cell growth and causes podocyte damage, which leads to glomerulosclerosis and tubulointerstitial fibrosis

This is also known as nodular panniculitis

It is crucial to follow their advice on whether to take the missed dose or wait until the next scheduled dose

A monthly supply at moderate doses for both compounds typically runs between $100 and $200 CAD, which is significantly less than prescription GLP-1 medications like Ozempic or Wegovy