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Accumulated iron in the substantia nigra binds to -synuclein with affinity, promoting its cytotoxic aggregation and increasing the number of reactive oxygen species (ROS) [46]

A multivariable logistic regression model showed that a higher frequency of red and processed meat consumption was significantly associated with an increased risk of thyroid autoimmunity, as indicated by TPOAb positivity

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Chronic inflammation promotes the production of ROS, exacerbating oxidative damage, which further extends cellular senescence and ferroptosis, leading to age-related pathologies

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Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes