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Although cells can withstand low levels of ROS, processes within mitochondria ensure that levels do not increase to unfavorable amounts, all without compromising the contribution of ROS to signaling pathways

Zheng, H., Wei, J., Wang, L., Wang, Q., Zhao, J., Chen, S., & Wei, F

Biomaterials 256, 120213

One proposed mechanism is that low B12 may influence adipogenic gene expression through hypomethylation [27], though further mechanistic studies are needed to confirm this pathway