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As Lee, Cell Metabolism reported, MOTS-c levels increase during metabolic stress, suggesting it serves as an adaptive response mechanism to restore cellular balance

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In mammals, CAC can accept acylcarnitines with acyl chains of various lengths from 2 to 18 carbon atoms as substrates, but it showed a higher affinity for acylcarnitines with longer carbon chains (Indiveri et al., 2011)

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