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Ensuring proper dosage, formulation accuracy, and compliance with regulatory standards is crucial to maintaining product efficacy and consumer safety

These studies do not address the use of ALA for managing NP and were not included in this review

In studies of human immunodeficiency virus (HIV)associated sensory neuropathy in individuals of black African ethnicity, two protective haplotypes correlated with reduced neuropathic pain risk were identified, which were a 3SNP haplotype (CAT, p = 0.02) and a 6SNP haplotype (CTCGAT, p = 0.04) [108]

However, whether these individual components directly contribute to the observed effects when present together in the formulation remains to be determined

10.1242/jcs.171017 J

Zaballos MA, Santisteban P