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Reducing energy intake (such as reducing food take) and/or increasing energy expenditure (such as increasing physical activity and/or non-shivering thermogenesis) offer promising strategies for combating obesity

Importantly, in active intestinal inflammation, HIF-2 may exert context-dependent effects on ferroptosis susceptibility: even under systemic iron deficiency, local inflammatory cues can paradoxically enhance epithelial iron uptake and/or perturb subcellular iron distribution, thereby increasing the labile iron pool and promoting lipid peroxidation

Current detection methods face challenges in achieving direct and sensitive identification of these compounds in food matrices

According to the latest assessment from the World Health Organization, more than half of the cases of blindness worldwide are attributed to cataracts (Organization, 2019)

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