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Its most critical roles include supporting the production of healthy red blood cells, DNA synthesis, strengthening the brain and nervous system, and enhancing immune function

Further mechanistic studies showed that ROS and lipofuscin levels, A aggregation, and toxicity were reduced after p -HBA treatment, suggesting that p -HBA ameliorated A-induced toxicity by enhancing antioxidant and anti-aging activity and inhibiting A aggregation

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Furthermore, in the study of the neuroprotective effect of mesenchymal stem cells on the regulation of oxidative stress on retinal nerves, it was also found that the expression of GPX6 was upregulated (Usategui-Martn et al., 2022)

although at the advanced stages of the disease the dying neurones and compromised blood-brain barrier may act as instigators

5.2.3 Potential applications of antioxidants in personalized therapy For possible applications in personalized therapy, future research can combine genomics and biomarker studies to explore individual patient responses to specific antioxidants