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NAD+/NADH and skeletal muscle mitochondrial adaptations to exercise

10) Hormonal and Endocrine Effects Because metabolic pathways interact closely with endocrine signaling, potential secondary hormonal effects may include: Thyroid function fluctuations Cortisol changes Insulin sensitivity alterations While some research suggests improved metabolic efficiency, endocrine dysregulation remains a theoretical concern without long-term human studies

Athletes report shortened recovery periods after high-intensity workouts or eccentric training phases

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Cell Death Dis 13 , 132 (2022)

Aspalathin is a CC-linked dihydrochalcone glucoside [176,177] and aspalalinin is a cyclic dihydrochalcone [178], and both are only isolated from rooibos