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Methylglyoxal induces reactive oxygen species formation The entanglement of the MGO detoxification pathway with the redox status, through affecting GSH availability and glyoxalase efficiency as explained prior, has implications for the ROS balance in BMECs exposed to MGO

doi: 10.1038/s41467-023-39245-3 35 SaitoY

Robert Wallace, Mr

Objective: To perform a review of existing literature on the safety and efficacy of topical glutathione

Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form