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Some users report a mild drop-off or return of symptoms after stopping, especially if: The underlying condition was not fully healed BPC-157 was used without addressing root causes (e.g., diet, stress, overtraining) They used lower doses or short durations without stacking foundational support like L-Glutamine or Collagen Protein This doesn't mean BPC-157 stopped workingrather, that the body still needs support to complete the healing process

Molecular mechanism studies revealed miR-495 induced senescence of MSCs via Bmi-1 [139]

doi: 10.1038/nature05127

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Proc Nat Acad Sci 108:14791483, 2011
