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The Journal of Pharmacology and Experimental Therapeutics
Mithaiwala MN, Santana-Coelho D, Porter GA, Oconnor JC (2021) Neuroinflammation and the kynurenine pathway in CNS disease: molecular mechanisms and therapeutic implications
Nanomedicine (Lond) 9(14):20992108
Nat Rev Drug Discov 9, 215236
By integrating patient-specific physiological data with mechanistic PK/PD models, digital twins enable real-time prediction of nanoparticle circulation, tissue accumulation, and clearance
The number of spermatogonia, spermatocytes, and sperm cells in the HFT group was significantly higher than that in the HFC group
