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This seems to relate with the downregulation of genes related to ECM organization, TGF-, and MMP signaling in fibroblasts during the resolution phase of acute injuries whereas in chronic scenarios, these genes remain upregulated

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[DOI] [PubMed] [Google Scholar] 232.Klicek R., Kolenc D., Suran J., Drmic D., Brcic L., Aralica G., Sever M., Holjevac J., Radic B., Turudic T., et al