metformin or glp 1 Comparing Glucagon‐like peptide‐1 receptor agonists versus in drug‐naive patients: A nationwide cohort study - Sørensen - 2024 - Journal of Diabetes Metformin vs. GLP-1 Receptor Agonists:
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First, GLP-1RA can activate the first messenger adenylate cyclase (AC) after binding to the receptor, which stimulates an increase in the secretion level of the intracellular second messenger cyclic adenosine phosphate (cAMP) and subsequently activates the intracellular secondary messenger protein kinase A (PKA) (48)
Bech EM, Pedersen SL, Jensen KJ
