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Notably, knockdown of Gdh1 in different mouse cell lines (HepaMP9-1, 3T3 and KL-155) did not alter AMPK expression (Extended Data Fig

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A small RCT (n=262) in the 1990s showed that NAC (600 mg twice daily for 6 months) attenuated the (self-reported) severity of influenza (A/H1N1 virus) influenza and influenza-like episodes (evaluated by the length of time in bed), particularly in elderly high-risk persons, compared to placebo.(8) There were no deaths and no cases of hospitalisation in either group

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