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These findings establish protein farnesylation as a central coordinator of AT function, with dysregulation leading to metabolic disease manifestations including impaired glucose uptake, altered lipid storage, and disrupted adipokine secretion ( Table 5 )

Dihexa and its parent compounds exhibit powerful synaptogenic and pro- cognitive/anti-dementia activities (see previous Examples)

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2017 [cited 2024 May 7];14:26906

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage