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Kwon CY, Cho IH, Park KS

Abstract The present study aims to investigate the newly synthesized organotin (IV) complex (2E, 2E) dibutylstannanediyl bis (4-(4-nitrophenyl) amino)-4-oxobut-2-enoate (DTN) for its anti-ulcer potential

This indicates that upregulation of endogenous polyamines, especially putrescine, serves as a critical mediator in BBB injury

J Biol Chem 250(4):14221426 Falkowski M, Maciejczyk M, Koprowicz T et al (2018) Whey protein concentrate wpc-80 improves antioxidant defense systems in the salivary glands of 14-month wistar rats

Another study shows that urate administration elevated its levels in the SOD1G85R-expressing Drosophila model of familial amyotrophic lateral sclerosis (fALS) by activating the Akt signaling pathway and the catalytic subunit of glutamate-cysteine ligase (64)

These include (i) a low-affinity pathway through CD163 by macrophages (50) and (ii) renal excretion which is accompanied by profound oxidative stress and organ damage (51, 52)