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Maurice N

linked GADD45 overexpression to promoter hypomethylation, affecting cisplatin sensitivity through the disruption of apoptotic pathways [108]

There was also a decrease in metabolic markers, including TMAO, which is associated with improved gut microbiota, oxidized low-density lipoprotein (OxLDL), and decreased oxidative stress, as evidenced by reduced dROM levels

A systematic review of GSH as an adjuvant therapy in Parkinson's disease identified one controlled trial 65 showing doubtful benefit

Sodium iodate (NaIO 3 ), a common oxidative stressor that induced the generation of intracellular ROS, has been extensively employed to model selective RPE cell damage

Such mitochondria-targeted antioxidants include Mitoquinone (MitoQ), MitoVitE (vitamin E), MitoPBN (CoQ and phenyl tert-butyl nitrone conjugate), and MitoTEMPO (SOD mimetic)