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The antiproliferative activity of GS was found to be supported by reduced levels of cyclin D1, cdc2, and simultaneous upregulation of cyclin-dependent kinase inhibitors p21 and p27 (Figure 3A

cDNA generation and RTqPCR cDNA was generated using random hexamers and SuperScript II reverse transcriptase (Invitrogen, 18064-014), according to the manufacturers protocol

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Amino acids promote lipid synthesis primarily through activation of mTORC1

5.4 Molecular responses and gene regulation Transcriptomic analyses show that osmotic stress upregulates genes for ion transporters (e.g.,Na + /H + antiporters), aquaporins, osmoprotectant biosynthesis, and molecularchaperones (Liu Z

R., Nielsen, H
